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The Ohio River Islands National Wildlife Refuge (ORINWR) is a National Wildlife Refuge (NWR) in non-contiguous sites consisting of islands along 362 miles (583 km) of the Ohio River, primarily (85% of acreage) in the U.S. state of West Virginia. There are also two islands that are located upstream in Beaver County, Pennsylvania, and a pair that are located downstream in Lewis County, Kentucky. Looking downstream, the refuge is currently located in parts of these counties: Beaver, Brooke, Ohio, Marshall, Wetzel, Tyler, Pleasants, Wood, Jackson, Mason, and Lewis. All counties are part of West Virginia, with the Pennsylvania and Kentucky exceptions that are mentioned above.